Russia insulin pills into the clinical trial

Posted by yukip on November 20, 2008 in Diabetes

According to the Institute of Waluyefu professor, the majority of patients with diabetes need daily insulin injections several times, to regulate their body’s glucose metabolism, lower blood sugar. However, the long insulin injections patients would feel pain. In order to solve this problem, the Russian experts developed the insulin pill. The tablets from the surface covered with a protective effect of water gel, water surface of the gel containing a number of polysaccharides. The human digestive system to prevent infiltration of water gel, the destruction of insulin, the researchers through chemical reactions to a variety of enzyme inhibitors in combination with water gel together. In this way, many of insulin could be under the protection of the rapid adoption of the esophagus, stomach, intestine into. As the water surface polysaccharide gel with the intestinal wall proteins a chemical reaction, so as to anchor the polysaccharide, the insulin pill to stay on in the intestinal wall. After insulin will gradually through the special structure of water gel, intestinal absorption into the blood, a therapeutic effect.

In addition, Russian experts under the principle of choice of both the “anchor” and the enzyme inhibitor - a function of the material type mucin eggs. This substance contained in the protein can withstand the attack of digestive enzymes, containing hydrocarbons could play a “anchor”. Scientific research personnel so that the egg type mucin containing insulin and the combination of water gel, made from a modified tablet. Waluyefu professor said that the first phase of clinical trials showed that patients with diabetes taking insulin four times daily tablet, could be achieved with daily injections of insulin-like effects. At present, the insulin pill are receiving a new trial. Is expected, new drugs are expected in a few years after listing.